The Detroit Lions will host the New Orleans Saints in the first game of the 2026 regular season. Both teams come into the matchup with 0‑0 records, making this a true season opener for each franchise. Ford Field in Detroit will be the venue, and the game will kick off at 1:00 PM EDT on September 13, 2026.
The contest will air on FOX, and DraftKings has set the betting line at Detroit -7 with an over/under of 49.5. This marks the beginning of the season’s slate, with each team looking to establish early momentum in their inaugural game.